Manel Esteller studies the genetic alterations of the diseases. He has participated in the development of medicines to treat the cancer and new technologies to research in this field.
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A more benevolent treatment for patients with liver transplants
In the 80s the university hospital Vall d'Hebrón was the first hospital in Spain to carry out a liver transplant. Since then, the team of research doctors led by Dr. Carlos Margarit -who passed away recently-, has followed up the clinical course...
To facilitate the cancer pleural diagnosis doctors realize an exploration in the toraxic cavity, this method is called thoracoscopic. Nevertheless, medical investigators of the UAB have observed that this invasive technique has often been unnecessary. For that reason, they realized a analized this case.
The doctoral thesis of Aïda Pujol has studied a variant of preimplantational genetic diagnosis during in vitro fertilization and embryonic development. She analysed the numerical irregularity of the chromosomes in the oocytes using the fluorescent in situ hybridisation (FISH) technique. This allowed her to identify the different mechanisms...
More accurate diagnosis thanks to molecular cytogenetic techniques
Cristina Hernando shows in her doctoral thesis the utility of the new technologies in Molecular Cytogenetics, which is helpful to the characterization of imbalance and genome reorganization in different tissues. This work shows new correlations...
The new knowledge about genetics together with the sophisticated skills of analysis helps the scientists to understand the carcinogenic process. The present study, made by investigators of the UAB, is an example of this work. By using the bladder carcinoma as a case study, they analyzed his chromosomal alterations and then compared with his...
Biophysicists at the UAB corner AIDS
A team of biophysicists at the UAB have discovered the molecular process involved in AIDS and present their results. In their laboratory they artificially recreated part of the viral process and their conclusions are interesting. Peptides, which enable the virus to fuse with our cells, have a...
The oral antibiotics are administered systematically before a colon surgery. But, is it really necessary this medication? Investigators of the Hospital Vall d'Hebron and UAB think that it is not. This categorical negative reflects the results of a study in which participated 300 people in this situation.
In his research, Jordi Camps Polo obtains interesting results on the chromosomal instability of tumor cells. His research, that focuses in the human colon cancer, has used molecular cytogenetics techniques for his analysis. This novel approach has revealed chromosomal alterations during the cellular division that were invisible up to now.
In the design of new medicines, it is very important to know how the proteins' functions are characterized. Sandra Izquierdo's doctoral thesis, "�cids (+) i (-) aminociclobutan-1-carbox�lics i la seva incorporaci� en �-p�ptids. Estudi sint�tic i estructural", studied how the secondary structures of the particles that form the proteins, the...
