To find out molecular mechanisms by which astrocytes regulate memory formation
To establish astrocytes as a therapeutic target in neurodegeneration
Uncover the regulation and role of fatty acid oxidation in the brain: does fatty acid oxidation shape astrocytic excitability, neuronal networks and cognitive funcions.
Gain knowledge about the impairment of fatty acid oxidation in APOE4 compared to APOE3 astrocytes to provide a therapeutic approach for Alzheimer’s.