Biosensors i Bioanàlisi
Linies de Recerca
L'equip de recerca és expert en química bioanalítica i biodetecció i estem centrats en el disseny de dispositius de biodetecció electroquímica i tecnologies emergents adequades a nivell comunitari i d'atenció primària per al diagnòstic clínic en el lloc d'atenció mèdica i la seguretat alimentària en entorns de recursos baixos.
Informació d'interès
ExoSens-PoC. Pruebas de características mejoradas para el diagnóstico precoz de enfermedad de Alzheimer. Isabel Pividori /Mercè Martí (CoIP). Ministerio de Ciencia e Innovación (MICINN). Proyectos de Prueba de Concepto 2022. Execució: Desembre 2022 - Desembre 2024.
AmpliSens. Pruebas rápidas de características mejoradas para el diagnóstico perinatal de GBS en mujeres embarazadas y sus bebés. Pividori Gurgo, M. I. (Investigadora principal). Ministerio de Ciencia e Innovación (MICINN): 47.552,00 €. Proyectos en Colaboración Pública-Privada 2021. Execució: Setembre 2022 – Agost 2024.
Sens4AD: Transforming Alzheimer's disease management: innovative diagnostics for better patient lives. Rossi ., R. (Investigadora principal), Marti Ripoll, M. M. (Investigadora), del Valle Peña, A. (Predoctoral) & Pividori Gurgo, M. I. (Avaladora). Ajuntament de Barcelona. Subvencions Recerca Jove i Emergent 2024.
EChiLiBRiST: Development and validation of a quantitative point-of-care test for the measurement of severity biomarkers to improve risk stratification of fever syndromes and enhance child survival. Pividori Gurgo, M. I. (Investigadora principal) & Marti Ripoll, M. M. (Investigadora). HORIZON-HLTH-2021-DISEASE-04. Execució: Setembre 2022 – Agost 2027
Sens4IVD. Biosensing devices for in vitro diagnostics. Isabel Pividori /Mercè Martí (CoIP). Ministerio de Ciencia e Innovación (MICINN). Proyectos Generación del Conocimiento. Execució: 1/09/23 – 31/08/26.
AviaSens. Rapid Test for Viral Outbreaks in Poultry Farms. Proyectos en Colaboración Pública-Privada 2023. Coordinador: BioEclosion SL. IP UAB: Isabel Pividori. Execució: Setembre 2023 – Agost 2026.
2024
Rapid diagnostic test for assessment of cellular immune response in a viral infection as a model. Mireia Bernuz, Juan Carlos Porras, Natalia Egri, Europa Azucena González-Navarro, Manel Juan, María Isabel Pividori, Mercè Martí, Sensors & Actuators: B. Chemical, Volume 417, 15 October 2024, 136185, https://doi.org/10.1016/j.snb.2024.136185
Carbon nanoparticle-based lateral flow assay for the detection of specific double-tagged DNA amplicons of Paracoccidioides spp. Javier Mussin, Gustavo Giusiano, Juan Carlos Porras, Luis Hernando Corredor Sanguña, María Isabel Pividori, Microchimica Acta (2024) 191:287 https://doi.org/10.1007/s00604-024-06367-4
Evaluating smartphone-based optical readouts for immunoassays in human and veterinary healthcare: A comparative study. Melania Mesas Gómez, Esther Julián, Lara Armengou, Maria Isabel Pividori, 275, 2024, 126106, https://doi.org/10.1016/j.talanta.2024.126106
Peptide-based biosensing approaches for targeting breast cancer-derived exosomes. Rafael da Fonseca Alves, Arnau Pallarès-Rusiñol, Rosanna Rossi, Merce Martí , Emilia Rezende Vaz, Thaise Gonçalves de Araújo, Maria Del Pilar Taboada Sotomayor and Maria Isabel Pividori. Biosensors and Bioelectronics 255, 2024, 116211. https://doi.org/10.1016/j.bios.2024.116211
Replication data for: “Peptide-based biosensing approaches for targeting breast cancer-derived exosomes”. Rafael da Fonseca Alves, Arnau Pallarès-Rusiñol, Rosanna Rossi, Merce Martí , Emilia Rezende Vaz, Thaise Gonçalves de Araújo, Maria Del Pilar Taboada Sotomayor and Maria Isabel Pividori. 2024 | Data set. DOI: 10.34810/data1273
Los exosomas. Nuevas herramientas para el diagnóstico de enfermedades no transmisibles en biopsias líquidas. Rosanna Rossi, Arnau Pallarès-Rusiñol, Mercé Martí, María Isabel Pividori. Actualidad Analítica 85, 2024, 15-20. ISSN 2444-8818. Sociedad española de química analítica.
Mycobacterium detection method combining filtration, immunomagnetic separation, and electrochemical readout in a portable biosensing device. Melania Mesas Gómez, Bárbara Molina-Moya, Bárbara Camila de Araújo, Arnau Pallarès-Rusiñol, Jofre Ferrer-Dalmau, Maria Valnice Boldrín Zanoni, José Domínguez, Esther Julian, María Isabel Pividori Gurgo. Sensors & Actuators: B. Chemical 403 (2024) 135211 https://doi.org/10.1016/j.snb.2023.135211
Experimental data of the manuscript “Mycobacterium detection method combining filtration, immunomagnetic separation, and electrochemical readout in a portable biosensing device”. Melania Mesas Gómez, Bárbara Molina-Moya, Bárbara Camila de Araújo, Arnau Pallarès-Rusiñol, Jofre Ferrer-Dalmau, Maria Valnice Boldrín Zanoni, José Domínguez, Esther Julian, María Isabel Pividori Gurgo. 2024 | Data set. DOI: 10.34810/DATA1016
Improved biosensing of Legionella by integrating filtration and immunomagnetic separation of the bacteria retained in filters. Melania Mesas Gómez, Bárbara Molina¿Moya, Bárbara de Araujo Souza, Maria Valnice Boldrin Zanoni, Esther Julián, José Domínguez, Maria Isabel Pividori. (2024). Microchimica Acta (2024) 191:82 https://doi.org/10.1007/s00604-023-06122-1
Experimental data of the manuscript “Improved biosensing of Legionella by integrating filtration and immunomagnetic separation of the bacteria retained in filters”. Melania Mesas Gómez, Bárbara Molina¿Moya, Bárbara de Araujo Souza, Maria Valnice Boldrin Zanoni, Esther Julián, José Domínguez, Maria Isabel Pividori. 2024 | Data set. DOI: 10.34810/data1015
2023
Magnetic Separation of Cell-Secreted Vesicles with Tailored Magnetic Particles and Downstream Applications. Bernuz, M., Pallarès-Rusiñol, A., Rossi, R., Fernández-Senac, C., Martí, M., Pividori, M.I. (2023). In: Vainio, S. (eds) Cell-Secreted Vesicles. ‘Methods in Molecular Biology’, vol 2668. Humana, New York, NY. https://doi.org/10.1007/978-1-0716-3203-1_18
Plasma extracellular vesicles reveal early molecular differences in amyloid positive patients with early-onset mild cognitive impairment. Amanda Cano, Pablo García, Mireia Bernuz, Raquel Puerta, Itziar de Rojas, Ester Esteban-De Antonio, Alba Pérez-Cordón, Laura Montreal, Raúl Núñez, Óscar Sotolongo-Grau, Silvia Alonso-Lana, Emilio Alarcón-Martín, Sergi Valero, Montserrat Alegret, Joan Martínez, Elvira Martín, Miren Ettcheto, Assumpta Vivas, Marta Gomez-Chiari, Miguel Ángel Tejero, Adelina Orellana, Lluís Tárraga, Marta Marquié, Mercè Martí, María Isabel Pividori, Mercè Boada, Agustín Ruiz, Journal of Nanobiotechnology 2023, 21 (1), 1-19. https://doi.org/10.1186/s12951-023-01793-7
Electrochemical genosensing of overexpressed GAPDH transcripts in breast cancer exosomes. A Pallarès Rusiñol, Lima de Moura, M Martí, MI Pividori. Electrochemical genosensing of overexpressed GAPDH transcripts in breast cancer exosomes. Analytical chemistry, 2023, 95, 2487–2495 https://doi.org/10.1021/acs.analchem.2c04773.
Experimental data of the manuscript “Electrochemical Genosensing of Overexpressed GAPDH Transcripts in Breast Cancer Exosomes”. A Pallarès Rusiñol, Lima de Moura, M Martí, MI Pividori. Electrochemical genosensing of overexpressed GAPDH transcripts in breast cancer exosomes. 2023 | Data set. DOI: 10.34810/DATA681.
Advances in exosome analysis. A Pallares-Rusiñol, M Bernuz, S L Moura, C Fernández-Senac, R Rossi, M Martí and MI Pividori, in Advances in Clinical Chemistry 2023,112:69-117 https://doi.org/10.1016/bs.acc.2022.09.002
Extracellular vesicles, the emerging mirrors of brain physiopathology. Cano A, Ettcheto M, Bernuz M, Puerta R, Esteban de Antonio E, Sánchez-López E, Souto EB, Camins A, Martí M, Pividori MI, Boada M, Ruiz A. International Journal of Biological Sciences 19(3):721-743. doi:10.7150/ijbs.79063
2022
Electrochemical glyphosate sensor based on hybrid material SiO2/Sm2O3/carbon modified with Meldola Blue. R. Blasques, A. Mendes A. Costa, T. Canevari, L.Arenas; (…) MI Pividori, Paulo Villis, Electroanalysis 2022, 34, 1– 13. https://doi.org/10.1002/elan.202200373
Sensitive Aptasensor Using Biotin-Streptavidin System for Patulin Detection in Apple Juice. Tang X, Zhang Q, Pividori MI, Zhang Z, Marty J-L, Catanante G. A. Biosensors. 2022; 12(2):59. https://doi.org/10.3390/bios12020059
The activity of alkaline phosphatase in breast cancer exosomes simplifies the biosensing design. Silio Lima de Moura, Arnau Pallarès Rusiñol, Luciano Sappia, Mercè Martí and MI Pividori. Biosensors and Bioelectronics 198, 113826. https://doi.org/10.1016/j.bios.2021.113826
Proteomic analyses of plasma exosomes reveal early molecular differences in the biomarkers profile of a cohort of early-onset mild cognitive impairment: the BIOFACE study. Amanda Cano, Pablo García, Mireia Bernuz, Raquel Puerta, Itziar de Rojas, Ester Esteban-De Antonio, Alba Pérez-Cordón, Laura Montreal, Raúl Núñez, Óscar Sotolongo-Grau, Silvia Alonso-Lana, Emilio Alarcón-Martín, Sergi Valero, Montserrat Alegret, Joan Martínez, Elvira Martín, Miren Ettcheto, Assumpta Vivas, Marta Gomez-Chiari, Miguel Ángel Tejero, Adelina Orellana, Lluís Tárraga, Marta Marquié, Mercè Martí, María Isabel Pividori, Mercè Boada, Agustín Ruiz, under review.
2021
Immunomagnetic separation improves the detection of mycobacteria by paper-based lateral and vertical flow immunochromatographic assays. A Ben Aissa, B Araújo, E Julián, MV Boldrin Zanoni and MI Pividori. Sensors 2021, 21(18), 5992; https://doi.org/10.3390/s21185992. Selected for the cover.
Magnetic-molecularly imprinted polymers in electrochemical sensors and biosensors. J. Marfà, R.R. Pupin, MPT Sotomayor & MI. Pividori. Analytical and Bioanalytical Chemistry 2021; https://doi.org/10.1007/s00216-021-03461-x
Development of magnetic nanoparticles modified with new molecularly imprinted polymer (MIPs) for selective analysis of glutathione. AC Ferreira Santos, ORP de Araújo, FA Moura, S Khan, AA Tanaka, AEG Santana, MI Pividori, MDPT Sotomayor, MOF Goulart. Sensors and Actuators B: Chemical, 2021, 344, 130171; https://doi.org/10.1016/j.snb.2021.130171.
Comparative Study of Gold and Carbon Nanoparticles in Nucleic Acid Lateral Flow Assay. Juan Carlos Porras, Mireia Bernuz, Jennifer Marfa, Arnau Pallares-Rusiñol, Mercè Martí and María Isabel Pividori, 2021, Nanomaterials 2021, 11(3), 741; https://doi.org/10.3390/nano11030741
Assessment of the biological potential of diaryltriazene-derived triazene compounds. Patricia de Maria Silva Figueirêdo, …, María Isabel Pividori, Manfredo Hörner & Paulo Cesar Mendes Villis. Scientific Reports volume 11, Article number: 2541 (2021).
Electrochemical Genosensing of E. coli Based on Padlock Probes and Rolling Circle Amplification. Alejandra Ben Aissa, Narayanan Madaboosi, Mats Nilsson and Maria Isabel Pividori, 2021, Sensors 2021, 21(5), 1749; https://doi.org/10.3390/s21051749
Immunomagnetic separation of Salmonella with tailored magnetic micro and nanocarriers. In Salmonella Methods and Protocols (third edition), ‘Methods in Molecular Biology’ by Humana Press, 2021, 2182:51-65. doi: 10.1007/978-1-0716-0791-6_7.
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